Local Resources For City of Cape Girardeau, MO Residents With over 40,559 residents, the city of Cape Girardeau, MO is spread over 1,395.70 square miles in beautiful state of Missouri. Here are useful links for our patients. ▸ City Alert Center: Click Here▸ City Website: Click Here▸ Hospitals: Click Here▸ Public Parks: Click Here▸ Banks: Click Here▸ Chamber of Commerce: Click Here 5 Doctors Park, Cape Girardeau, MO 63703
